Höti, Naseruddin <br/><br/>
p53-dependent apoptotic mechanism of a new designer bimetallic compound tri-phenyl tin benzimidazolethiol copper chloride (TPT-CuCl2): in vivo studies in Wistar rats as well as in vitro studies in human cervical cancer cells.  [electronic resource] 

 -  The Journal of pharmacology and experimental therapeutics  Oct 2004 
 - 22-33 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0022-3565 
<br/><br/><label>Standard No.: </label>10.1124/jpet.104.069104  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Apoptosis<br/>Apoptosis Regulatory Proteins<br/>Carrier Proteins--metabolism<br/>Caspase 3<br/>Caspases--metabolism<br/>Cell Division--drug effects<br/>Cytochromes c--metabolism<br/>Down-Regulation<br/>Enzyme Activation<br/>Female<br/>HeLa Cells<br/>Humans<br/>Inhibitor of Apoptosis Proteins<br/>Intracellular Signaling Peptides and Proteins<br/>Membrane Proteins--metabolism<br/>Microtubule-Associated Proteins--metabolism<br/>Mitochondria--drug effects<br/>Mitochondrial Proteins--metabolism<br/>Neoplasm Proteins<br/>Organotin Compounds--pharmacology<br/>Papillomaviridae--drug effects<br/>Proto-Oncogene Proteins c-bcl-2--metabolism<br/>Rats<br/>Rats, Wistar<br/>Survivin<br/>Tumor Suppressor Protein p53--metabolism<br/>Uterine Cervical Neoplasms--pathology<br/>bcl-2 Homologous Antagonist-Killer Protein<br/>bcl-2-Associated X Protein