Candidate topical microbicides bind herpes simplex virus glycoprotein B and prevent viral entry and cell-to-cell spread. [electronic resource]
- Antimicrobial agents and chemotherapy Jun 2004
- 2025-36 p. digital
Publication Type: Historical Article; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0066-4804
10.1128/AAC.48.6.2025-2036.2004 doi
Anti-Infective Agents, Local--pharmacology Body Fluids--chemistry Cell Line Cell Survival--drug effects Cervix Uteri--metabolism Cytokines--biosynthesis Dose-Response Relationship, Drug Epithelial Cells--drug effects Female Herpes Simplex--drug therapy Herpesvirus 2, Human--pathogenicity History, 17th Century Humans Hydrogen-Ion Concentration Kinetics Polysaccharides--pharmacology Protein Binding Surface Plasmon Resonance Viral Envelope Proteins--metabolism Viral Plaque Assay