TY - GEN AU - Siu,Wai Yi AU - Lau,Anita AU - Arooz,Talha AU - Chow,Jeremy P H AU - Ho,Horace T B AU - Poon,Randy Y C TI - Topoisomerase poisons differentially activate DNA damage checkpoints through ataxia-telangiectasia mutated-dependent and -independent mechanisms SN - 1535-7163 PY - 2005///0111 KW - Antibiotics, Antineoplastic KW - pharmacology KW - Ataxia Telangiectasia Mutated Proteins KW - Caffeine KW - Camptothecin KW - antagonists & inhibitors KW - Cell Cycle KW - drug effects KW - Cell Cycle Proteins KW - metabolism KW - Cell Death KW - Cell Line, Tumor KW - DNA Damage KW - DNA-Binding Proteins KW - Dose-Response Relationship, Drug KW - Doxorubicin KW - Enzyme Inhibitors KW - G1 Phase KW - G2 Phase KW - Genes, cdc KW - Guanine Nucleotide Exchange Factors KW - Humans KW - Nuclear Proteins KW - Protein Serine-Threonine Kinases KW - deficiency KW - S Phase KW - Topoisomerase I Inhibitors KW - Topoisomerase II Inhibitors KW - Tumor Suppressor Proteins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't ER -