Olanzapine produces trophic effects in vitro and stimulates phosphorylation of Akt/PKB, ERK1/2, and the mitogen-activated protein kinase p38. [electronic resource]
- Brain research Jun 2004
- 58-68 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
0006-8993
10.1016/j.brainres.2004.03.018 doi
3-Phosphoinositide-Dependent Protein Kinases Amyloid beta-Peptides--pharmacology Animals Antipsychotic Agents--pharmacology Benzodiazepines--pharmacology Blotting, Western--methods Bromodeoxyuridine--metabolism Cell Division--drug effects Cells, Cultured Cerebral Cortex--cytology Culture Media, Serum-Free--pharmacology Dose-Response Relationship, Drug Drug Interactions Enzyme Activation--drug effects Enzyme Inhibitors--pharmacology Humans Mice Mitogen-Activated Protein Kinase 1--metabolism Mitogen-Activated Protein Kinase 3 Mitogen-Activated Protein Kinases--metabolism Neuroblastoma Neurons--drug effects Olanzapine Peptide Fragments--pharmacology Pertussis Toxin--pharmacology Phosphorylation--drug effects Protein Serine-Threonine Kinases--metabolism Rats Tetrazolium Salts Thiazoles Time Factors p38 Mitogen-Activated Protein Kinases