Smith-Jones, Peter M <br/><br/>
Imaging the pharmacodynamics of HER2 degradation in response to Hsp90 inhibitors.  [electronic resource] 

 -  Nature biotechnology  Jun 2004 
 - 701-6 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>1087-0156 
<br/><br/><label>Standard No.: </label>10.1038/nbt968  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antibodies, Monoclonal--chemistry<br/>Antibodies, Monoclonal, Humanized<br/>Antineoplastic Agents--chemistry<br/>Benzoquinones<br/>Blotting, Western<br/>Cell Line, Tumor<br/>Copper Radioisotopes<br/>Female<br/>HSP90 Heat-Shock Proteins--antagonists & inhibitors<br/>Heterocyclic Compounds, 1-Ring--chemistry<br/>Humans<br/>Immunoblotting<br/>Immunoglobulin Fab Fragments--chemistry<br/>Indium Radioisotopes<br/>Isotope Labeling<br/>Lactams, Macrocyclic<br/>Mice<br/>Mice, Nude<br/>Molecular Probe Techniques<br/>Neoplasms--chemistry<br/>Phosphatidylinositol 3-Kinases--metabolism<br/>Positron-Emission Tomography--methods<br/>Protein Serine-Threonine Kinases--antagonists & inhibitors<br/>Receptor, ErbB-2--drug effects<br/>Rifabutin--analogs & derivatives<br/>Tissue Distribution<br/>Trastuzumab<br/>Xenograft Model Antitumor Assays