TY - GEN AU - Hoivik,Debie J AU - Qualls,Charles W AU - Mirabile,Rosanna C AU - Cariello,Neal F AU - Kimbrough,Carie L AU - Colton,Heidi M AU - Anderson,Steven P AU - Santostefano,Michael J AU - Morgan,Ronda J Ott AU - Dahl,Ray R AU - Brown,Alan R AU - Zhao,Zhiyang AU - Mudd,Paul N AU - Oliver,William B AU - Brown,H Roger AU - Miller,Richard T TI - Fibrates induce hepatic peroxisome and mitochondrial proliferation without overt evidence of cellular proliferation and oxidative stress in cynomolgus monkeys SN - 0143-3334 PY - 2004///1005 KW - Acyl-CoA Oxidase KW - metabolism KW - Animals KW - Apoptosis KW - Area Under Curve KW - Catalase KW - genetics KW - Cell Division KW - drug effects KW - Clofibric Acid KW - analogs & derivatives KW - Cyclin D1 KW - Cyclin-Dependent Kinase Inhibitor p21 KW - Cyclins KW - Endoplasmic Reticulum, Smooth KW - Fenofibrate KW - toxicity KW - Fibric Acids KW - Gene Expression Profiling KW - Glutathione Peroxidase KW - Liver KW - cytology KW - Macaca fascicularis KW - Male KW - Mitochondria KW - Mitotic Index KW - Organ Size KW - Oxidative Stress KW - Peroxisomes KW - Proliferating Cell Nuclear Antigen KW - RNA, Messenger KW - Receptors, Cytoplasmic and Nuclear KW - Thioredoxin-Disulfide Reductase KW - Transcription Factors N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1093/carcin/bgh182 ER -