TY - GEN AU - Betts,Michael R AU - Price,David A AU - Brenchley,Jason M AU - Loré,Karin AU - Guenaga,F Javier AU - Smed-Sorensen,Anna AU - Ambrozak,David R AU - Migueles,Stephen A AU - Connors,Mark AU - Roederer,Mario AU - Douek,Daniel C AU - Koup,Richard A TI - The functional profile of primary human antiviral CD8+ T cell effector activity is dictated by cognate peptide concentration SN - 0022-1767 PY - 2004///0902 KW - Antigens KW - metabolism KW - CD8-Positive T-Lymphocytes KW - immunology KW - Cell Degranulation KW - Cell Separation KW - Clone Cells KW - Cytokines KW - biosynthesis KW - Cytomegalovirus KW - Cytotoxicity, Immunologic KW - Dose-Response Relationship, Immunologic KW - Epitopes, T-Lymphocyte KW - Gene Rearrangement, beta-Chain T-Cell Antigen Receptor KW - HIV-1 KW - HLA-A2 Antigen KW - Humans KW - Interferon-gamma KW - Lymphocyte Activation KW - Lymphocyte Count KW - Peptides KW - Protein Binding KW - Receptors, Antigen, T-Cell KW - antagonists & inhibitors KW - Viral Proteins N1 - Publication Type: Journal Article UR - https://doi.org/10.4049/jimmunol.172.10.6407 ER -