Mühlethaler-Mottet, Annick <br/><br/>
Drug-mediated sensitization to TRAIL-induced apoptosis in caspase-8-complemented neuroblastoma cells proceeds via activation of intrinsic and extrinsic pathways and caspase-dependent cleavage of XIAP, Bcl-xL and RIP.  [electronic resource] 

 -  Oncogene  Jul 2004 
 - 5415-25 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0950-9232 
<br/><br/><label>Standard No.: </label>10.1038/sj.onc.1207704  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--pharmacology<br/>Apoptosis--drug effects<br/>Apoptosis Regulatory Proteins<br/>Caspase 8<br/>Caspases--metabolism<br/>Cycloheximide--pharmacology<br/>Humans<br/>Membrane Glycoproteins--pharmacology<br/>Mitochondria--drug effects<br/>Neuroblastoma--drug therapy<br/>Protein Synthesis Inhibitors--pharmacology<br/>Proteins--metabolism<br/>Proto-Oncogene Proteins c-bcl-2--metabolism<br/>Receptor-Interacting Protein Serine-Threonine Kinases<br/>Receptors, TNF-Related Apoptosis-Inducing Ligand<br/>Receptors, Tumor Necrosis Factor--biosynthesis<br/>TNF-Related Apoptosis-Inducing Ligand<br/>Tumor Cells, Cultured<br/>Tumor Necrosis Factor-alpha--pharmacology<br/>X-Linked Inhibitor of Apoptosis Protein<br/>bcl-X Protein