TY - GEN AU - Hirai,Kiyoshi AU - Hayashi,Takeshi AU - Chan,Pak H AU - Zeng,Jianying AU - Yang,Guo-Yuan AU - Basus,Vladimir J AU - James,Thomas L AU - Litt,Lawrence TI - PI3K inhibition in neonatal rat brain slices during and after hypoxia reduces phospho-Akt and increases cytosolic cytochrome c and apoptosis SN - 0169-328X PY - 2004///0628 KW - Animals KW - Animals, Newborn KW - Apoptosis KW - physiology KW - Brain KW - cytology KW - Carrier Proteins KW - metabolism KW - Chaperonin 60 KW - Chromones KW - pharmacology KW - Cytochromes c KW - Cytosol KW - DNA Fragmentation KW - Enzyme Inhibitors KW - Enzyme-Linked Immunosorbent Assay KW - methods KW - Fluorescent Antibody Technique KW - Hypoxia KW - enzymology KW - In Situ Nick-End Labeling KW - In Vitro Techniques KW - Magnetic Resonance Imaging KW - Mitochondria KW - drug effects KW - Morpholines KW - Neural Inhibition KW - Neurons KW - Phosphoinositide-3 Kinase Inhibitors KW - Phosphorus Isotopes KW - Phosphorylation KW - Protein Serine-Threonine Kinases KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-akt KW - Rats KW - Rats, Sprague-Dawley KW - Serine KW - Staining and Labeling KW - Time Factors KW - bcl-Associated Death Protein N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1016/j.molbrainres.2004.02.009 ER -