TY  - GEN
AU  - Bourguignon,Lilly Y W
AU  - Singleton,Patrick A
AU  - Diedrich,Falko
AU  - Stern,Robert
AU  - Gilad,Eli
TI  - CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion
SN  - 0021-9258
PY  - 2004///0813
KW  - Amides
KW  - pharmacology
KW  - Amiloride
KW  - analogs & derivatives
KW  - Animals
KW  - Breast Neoplasms
KW  - enzymology
KW  - Cathepsin B
KW  - metabolism
KW  - Caveolin 1
KW  - Caveolins
KW  - Cell Line, Tumor
KW  - Endosomes
KW  - Enzyme Inhibitors
KW  - Humans
KW  - Hyaluronan Receptors
KW  - chemistry
KW  - Hyaluronic Acid
KW  - Hyaluronoglucosaminidase
KW  - genetics
KW  - Hydrogen-Ion Concentration
KW  - Immunoglobulin G
KW  - Intracellular Signaling Peptides and Proteins
KW  - Lysosomes
KW  - Membrane Microdomains
KW  - Membrane Proteins
KW  - Neoplasm Invasiveness
KW  - Phosphorylation
KW  - Protein Serine-Threonine Kinases
KW  - antagonists & inhibitors
KW  - Pyridines
KW  - RNA, Small Interfering
KW  - Rats
KW  - Sodium-Hydrogen Exchangers
KW  - rho-Associated Kinases
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1074/jbc.M311838200
ER  -