Bourguignon, Lilly Y W <br/><br/>
CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion.  [electronic resource] 

 -  The Journal of biological chemistry  Jun 2004 
 - 26991-7007 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0021-9258 
<br/><br/><label>Standard No.: </label>10.1074/jbc.M311838200  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amides--pharmacology<br/>Amiloride--analogs & derivatives<br/>Animals<br/>Breast Neoplasms--enzymology<br/>Cathepsin B--metabolism<br/>Caveolin 1<br/>Caveolins--metabolism<br/>Cell Line, Tumor<br/>Endosomes--metabolism<br/>Enzyme Inhibitors--pharmacology<br/>Humans<br/>Hyaluronan Receptors--chemistry<br/>Hyaluronic Acid--metabolism<br/>Hyaluronoglucosaminidase--genetics<br/>Hydrogen-Ion Concentration<br/>Immunoglobulin G--pharmacology<br/>Intracellular Signaling Peptides and Proteins<br/>Lysosomes--metabolism<br/>Membrane Microdomains--chemistry<br/>Membrane Proteins--metabolism<br/>Neoplasm Invasiveness<br/>Phosphorylation<br/>Protein Serine-Threonine Kinases--antagonists & inhibitors<br/>Pyridines--pharmacology<br/>RNA, Small Interfering--pharmacology<br/>Rats<br/>Sodium-Hydrogen Exchangers--antagonists & inhibitors<br/>rho-Associated Kinases