TY - GEN AU - Werneburg,Nate AU - Guicciardi,M Eugenia AU - Yin,Xiao-Ming AU - Gores,Gregory J TI - TNF-alpha-mediated lysosomal permeabilization is FAN and caspase 8/Bid dependent SN - 0193-1857 PY - 2004///0830 KW - Adaptor Proteins, Signal Transducing KW - Animals KW - Apoptosis KW - physiology KW - BH3 Interacting Domain Death Agonist Protein KW - Carrier Proteins KW - genetics KW - Caspase 8 KW - Caspases KW - metabolism KW - Cathepsin B KW - Cells, Cultured KW - Dactinomycin KW - pharmacology KW - Enzyme Activation KW - drug effects KW - Fas-Associated Death Domain Protein KW - Green Fluorescent Proteins KW - Intracellular Signaling Peptides and Proteins KW - Luminescent Proteins KW - Lysosomes KW - Mice KW - Mice, Knockout KW - Permeability KW - Proteins KW - Rats KW - Recombinant Fusion Proteins KW - Tumor Necrosis Factor-alpha N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1152/ajpgi.00019.2004 ER -