Weber, David S

Phosphoinositide-dependent kinase 1 and p21-activated protein kinase mediate reactive oxygen species-dependent regulation of platelet-derived growth factor-induced smooth muscle cell migration. [electronic resource] - Circulation research May 2004 - 1219-26 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1524-4571

10.1161/01.RES.0000126848.54740.4A doi


3-Phosphoinositide-Dependent Protein Kinases
Acetylcysteine--pharmacology
Animals
Aorta, Thoracic--cytology
Azoles--pharmacology
Becaplermin
Cell Movement--drug effects
Cells, Cultured--drug effects
Enzyme Activation--drug effects
Humans
Isoindoles
Mitogen-Activated Protein Kinase 1--physiology
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinases--physiology
Muscle, Smooth, Vascular--cytology
Myocytes, Smooth Muscle--drug effects
Organoselenium Compounds--pharmacology
Phosphorylation--drug effects
Platelet-Derived Growth Factor--pharmacology
Protein Processing, Post-Translational--drug effects
Protein Serine-Threonine Kinases--genetics
Proto-Oncogene Proteins c-sis
Rats
Reactive Oxygen Species--pharmacology
Receptors, Platelet-Derived Growth Factor--drug effects
Recombinant Fusion Proteins--pharmacology
Signal Transduction--drug effects
p21-Activated Kinases
rac GTP-Binding Proteins--physiology
src-Family Kinases--antagonists & inhibitors