TY  - GEN
AU  - Mehrotra,Mukund M
AU  - Heath,Julie A
AU  - Smyth,Mark S
AU  - Pandey,Anjali
AU  - Rose,Jack W
AU  - Seroogy,Joseph M
AU  - Volkots,Deborah L
AU  - Nannizzi-Alaimo,Lisa
AU  - Park,Gary L
AU  - Lambing,Joseph L
AU  - Hollenbach,Stanley J
AU  - Scarborough,Robert M
TI  - Discovery of novel 2,8-diazaspiro[4.5]decanes as orally active glycoprotein IIb-IIIa antagonists
SN  - 0022-2623
PY  - 2004///0519
KW  - Administration, Oral
KW  - Alkanes
KW  - chemical synthesis
KW  - Animals
KW  - Aza Compounds
KW  - Binding, Competitive
KW  - Biological Availability
KW  - Bleeding Time
KW  - Dogs
KW  - Humans
KW  - Hydantoins
KW  - Hydroxylamines
KW  - In Vitro Techniques
KW  - Lactams
KW  - Macaca fascicularis
KW  - Mice
KW  - Platelet Aggregation Inhibitors
KW  - Platelet Glycoprotein GPIIb-IIIa Complex
KW  - antagonists & inhibitors
KW  - Prodrugs
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Spiro Compounds
KW  - Structure-Activity Relationship
KW  - Urea
KW  - analogs & derivatives
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm030354b
ER  -