Guillon, Jean

Synthesis, antimalarial activity, and molecular modeling of new pyrrolo[1,2-a]quinoxalines, bispyrrolo[1,2-a]quinoxalines, bispyrido[3,2-e]pyrrolo[1,2-a]pyrazines, and bispyrrolo[1,2-a]thieno[3,2-e]pyrazines. [electronic resource] - Journal of medicinal chemistry Apr 2004 - 1997-2009 p. digital

Publication Type: Journal Article

0022-2623

10.1021/jm0310840 doi


Animals
Antimalarials--chemical synthesis
Cell Line
Crystallography, X-Ray
Drug Resistance
Erythrocytes--parasitology
Hemeproteins--chemistry
Humans
In Vitro Techniques
Models, Molecular
Plasmodium falciparum--drug effects
Protein Binding
Pyrazines--chemical synthesis
Pyridines--chemical synthesis
Pyrroles--chemical synthesis
Quinoxalines--chemical synthesis
Rats
Structure-Activity Relationship