Laudon, Hanna <br/><br/>
Functional domains in presenilin 1: the Tyr-288 residue controls gamma-secretase activity and endoproteolysis.  [electronic resource] 

 -  The Journal of biological chemistry  Jun 2004 
 - 23925-32 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0021-9258 
<br/><br/><label>Standard No.: </label>10.1074/jbc.M401277200  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Alanine--chemistry<br/>Amino Acid Sequence<br/>Amyloid Precursor Protein Secretases<br/>Animals<br/>Aspartic Acid Endopeptidases<br/>Cells, Cultured<br/>Embryo, Mammalian--cytology<br/>Endopeptidases--metabolism<br/>Enzyme-Linked Immunosorbent Assay<br/>Genes, Reporter<br/>Immunoblotting<br/>Luciferases--metabolism<br/>Membrane Proteins--chemistry<br/>Mice<br/>Molecular Sequence Data<br/>Mutagenesis, Site-Directed<br/>Mutation<br/>Precipitin Tests<br/>Presenilin-1<br/>Protein Structure, Tertiary<br/>Stem Cells--cytology<br/>Subcellular Fractions<br/>Transfection<br/>Tyrosine--chemistry