TY - GEN AU - Laudon,Hanna AU - Mathews,Paul M AU - Karlström,Helena AU - Bergman,Anna AU - Farmery,Mark R AU - Nixon,Ralph A AU - Winblad,Bengt AU - Gandy,Samuel E AU - Lendahl,Urban AU - Lundkvist,Johan AU - Näslund,Jan TI - Co-expressed presenilin 1 NTF and CTF form functional gamma-secretase complexes in cells devoid of full-length protein SN - 0022-3042 PY - 2004///0426 KW - Amyloid Precursor Protein Secretases KW - Amyloid beta-Peptides KW - metabolism KW - Animals KW - Aspartic Acid Endopeptidases KW - Blastocyst KW - cytology KW - Catalytic Domain KW - genetics KW - Cell Line KW - Endopeptidases KW - Enzyme Activation KW - Genes, Reporter KW - Macromolecular Substances KW - Membrane Glycoproteins KW - Membrane Proteins KW - Mice KW - Peptide Fragments KW - Presenilin-1 KW - Recombinant Fusion Proteins KW - Sequence Deletion KW - Stem Cells KW - Structure-Activity Relationship N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1046/j.1471-4159.2003.02298.x ER -