Ghilardi, Joseph R

Constitutive spinal cyclooxygenase-2 participates in the initiation of tissue injury-induced hyperalgesia. [electronic resource] - The Journal of neuroscience : the official journal of the Society for Neuroscience Mar 2004 - 2727-32 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

1529-2401

10.1523/JNEUROSCI.5054-03.2004 doi


Animals
Blotting, Western
Cyclooxygenase 2
Cyclooxygenase 2 Inhibitors
Cyclooxygenase Inhibitors--pharmacology
Disease Models, Animal
Hindlimb--injuries
Hyperalgesia--drug therapy
Immunohistochemistry
Injections, Spinal
Isoenzymes--antagonists & inhibitors
Lumbosacral Region
Male
N-Methylaspartate--pharmacology
Neuroglia--enzymology
Neurons--drug effects
Physical Stimulation
Prostaglandin-Endoperoxide Synthases--metabolism
Prostaglandins--metabolism
Proto-Oncogene Proteins c-fos--metabolism
Rats
Rats, Sprague-Dawley
Spinal Cord--drug effects
Substance P--metabolism
Up-Regulation