TY - GEN AU - Balle,Thomas AU - Halldin,Christer AU - Andersen,Linus AU - Hjorth Alifrangis,Lene AU - Badolo,Lassina AU - Gjervig Jensen,Klaus AU - Chou,Yuan-Wha AU - Andersen,Kim AU - Perregaard,Jens AU - Farde,Lars TI - New alpha(1)-adrenoceptor antagonists derived from the antipsychotic sertindole - carbon-11 labelling and pet examination of brain uptake in the cynomolgus monkey SN - 0969-8051 PY - 2004///1221 KW - ATP Binding Cassette Transporter, Subfamily B, Member 1 KW - deficiency KW - Adrenergic alpha-1 Receptor Antagonists KW - Animals KW - Antipsychotic Agents KW - chemistry KW - Brain KW - diagnostic imaging KW - Caco-2 Cells KW - Carbon Radioisotopes KW - Cyclosporine KW - pharmacology KW - Drug Evaluation, Preclinical KW - Humans KW - Imidazoles KW - Indoles KW - Isotope Labeling KW - methods KW - Kinetics KW - Macaca fascicularis KW - Male KW - Metabolic Clearance Rate KW - Mice KW - Positron-Emission Tomography KW - Protein Binding KW - Radiopharmaceuticals KW - chemical synthesis KW - Receptors, Adrenergic, alpha-1 KW - metabolism N1 - Publication Type: Comparative Study; Evaluation Study; Journal Article UR - https://doi.org/10.1016/j.nucmedbio.2003.08.012 ER -