TY - GEN AU - van Bezooijen,Rutger L AU - Roelen,Bernard A J AU - Visser,Annemieke AU - van der Wee-Pals,Lianne AU - de Wilt,Edwin AU - Karperien,Marcel AU - Hamersma,Herman AU - Papapoulos,Socrates E AU - ten Dijke,Peter AU - Löwik,Clemens W G M TI - Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist SN - 0022-1007 PY - 2004///0916 KW - Adaptor Proteins, Signal Transducing KW - Alkaline Phosphatase KW - metabolism KW - Animals KW - Bone Development KW - physiology KW - Bone Diseases, Developmental KW - Bone Morphogenetic Proteins KW - genetics KW - Cells, Cultured KW - DNA Primers KW - DNA, Complementary KW - DNA-Binding Proteins KW - Disease Models, Animal KW - Gene Expression Regulation, Developmental KW - Genetic Markers KW - Glycoproteins KW - Homeodomain Proteins KW - Humans KW - Immunohistochemistry KW - In Situ Hybridization KW - Intercellular Signaling Peptides and Proteins KW - Luciferases KW - Mice KW - Osteoblasts KW - Phosphorylation KW - Reverse Transcriptase Polymerase Chain Reaction KW - Smad Proteins KW - Trans-Activators KW - Transfection N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1084/jem.20031454 ER -