TY  - GEN
AU  - Watanabe,Ayahisa
AU  - Nagai,Junya
AU  - Adachi,Yoshinori
AU  - Katsube,Takayuki
AU  - Kitahara,Yasumi
AU  - Murakami,Teruo
AU  - Takano,Mikihisa
TI  - Targeted prevention of renal accumulation and toxicity of gentamicin by aminoglycoside binding receptor antagonists
SN  - 0168-3659
PY  - 2005///0114
KW  - Acetylglucosaminidase
KW  - antagonists & inhibitors
KW  - Aminoglycosides
KW  - administration & dosage
KW  - Animals
KW  - Aprotinin
KW  - pharmacology
KW  - Binding Sites
KW  - drug effects
KW  - Cells, Cultured
KW  - Cytochromes c
KW  - chemistry
KW  - Dehydration
KW  - drug therapy
KW  - Disease Models, Animal
KW  - Dose-Response Relationship, Drug
KW  - Drug Delivery Systems
KW  - methods
KW  - Drug Evaluation, Preclinical
KW  - Drug Therapy, Combination
KW  - Endocytosis
KW  - Gentamicins
KW  - adverse effects
KW  - Japan
KW  - Kidney Cortex
KW  - Kidney Tubules, Proximal
KW  - cytology
KW  - Low Density Lipoprotein Receptor-Related Protein-2
KW  - Male
KW  - Mice
KW  - Mice, Inbred Strains
KW  - Muramidase
KW  - Nerve Tissue Proteins
KW  - Peptide Fragments
KW  - chemical synthesis
KW  - Peptides
KW  - Rats
KW  - Rats, Wistar
KW  - Receptors, Drug
KW  - Species Specificity
KW  - Tissue Distribution
KW  - Tritium
N1  - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.jconrel.2003.12.005
ER  -