A novel dysfunctional growth hormone variant (Ile179Met) exhibits a decreased ability to activate the extracellular signal-regulated kinase pathway. [electronic resource]
- The Journal of clinical endocrinology and metabolism Mar 2004
- 1068-75 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-972X
10.1210/jc.2003-030652 doi
Body Height--genetics Child Crystallography, X-Ray Genetic Testing Growth Disorders--genetics Human Growth Hormone--chemistry Humans MAP Kinase Signaling System--physiology Mitogen-Activated Protein Kinases--metabolism Point Mutation Promoter Regions, Genetic--genetics Protein Structure, Tertiary