TY - GEN AU - Roberts,Reade B AU - Arteaga,Carlos L AU - Threadgill,David W TI - Modeling the cancer patient with genetically engineered mice: prediction of toxicity from molecule-targeted therapies SN - 1535-6108 PY - 2004///0517 KW - Animals KW - Antibodies, Monoclonal KW - adverse effects KW - Antibodies, Monoclonal, Humanized KW - Antineoplastic Agents KW - Benzamides KW - Cardiomyoplasty KW - Colorectal Neoplasms KW - drug therapy KW - Cyclooxygenase 2 KW - Disease Models, Animal KW - ErbB Receptors KW - antagonists & inhibitors KW - Gastrointestinal Diseases KW - chemically induced KW - Genes, abl KW - physiology KW - Genetic Engineering KW - Humans KW - Imatinib Mesylate KW - Isoenzymes KW - Membrane Proteins KW - Mice KW - Mice, Transgenic KW - genetics KW - Neoplasms KW - Piperazines KW - Prostaglandin-Endoperoxide Synthases KW - metabolism KW - Pyrimidines KW - Receptors, Platelet-Derived Growth Factor KW - Receptors, Transforming Growth Factor beta KW - Skin Abnormalities KW - Trastuzumab KW - Vascular Endothelial Growth Factor A N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Review UR - https://doi.org/10.1016/s1535-6108(04)00032-7 ER -