Roberts, Reade B
Modeling the cancer patient with genetically engineered mice: prediction of toxicity from molecule-targeted therapies. [electronic resource]
- Cancer cell Feb 2004
- 115-20 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Review
ISSN: 1535-6108
Standard No.: 10.1016/s1535-6108(04)00032-7 doi
Subjects--Topical Terms: Animals Antibodies, Monoclonal--adverse effects Antibodies, Monoclonal, Humanized Antineoplastic Agents--adverse effects Benzamides Cardiomyoplasty Colorectal Neoplasms--drug therapy Cyclooxygenase 2 Disease Models, Animal ErbB Receptors--antagonists & inhibitors Gastrointestinal Diseases--chemically induced Genes, abl--physiology Genetic Engineering Humans Imatinib Mesylate Isoenzymes--antagonists & inhibitors Membrane Proteins Mice Mice, Transgenic--genetics Neoplasms--drug therapy Piperazines--adverse effects Prostaglandin-Endoperoxide Synthases--metabolism Pyrimidines--adverse effects Receptors, Platelet-Derived Growth Factor Receptors, Transforming Growth Factor beta--antagonists & inhibitors Skin Abnormalities--chemically induced Trastuzumab Vascular Endothelial Growth Factor A--antagonists & inhibitors