TY  - GEN
AU  - Zhang,Donglei
AU  - Bar-Eli,Menashe
AU  - Meloche,Sylvain
AU  - Brodt,Pnina
TI  - Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals
SN  - 0021-9258
PY  - 2004///0615
KW  - Androstadienes
KW  - pharmacology
KW  - Animals
KW  - Blotting, Western
KW  - Carcinoma, Lewis Lung
KW  - metabolism
KW  - Cell Line, Tumor
KW  - Chloramphenicol O-Acetyltransferase
KW  - Chromones
KW  - Enzyme Activation
KW  - Enzyme Inhibitors
KW  - Extracellular Matrix
KW  - Flavonoids
KW  - Gene Expression Regulation, Enzymologic
KW  - Genes, Dominant
KW  - Genes, Reporter
KW  - Insulin-Like Growth Factor I
KW  - Matrix Metalloproteinase 2
KW  - biosynthesis
KW  - Mice
KW  - Mitogen-Activated Protein Kinases
KW  - Models, Biological
KW  - Morpholines
KW  - PTEN Phosphohydrolase
KW  - Phosphatidylinositol 3-Kinases
KW  - Phosphoric Monoester Hydrolases
KW  - Plasmids
KW  - Proto-Oncogene Proteins c-raf
KW  - RNA, Messenger
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Signal Transduction
KW  - Sirolimus
KW  - Time Factors
KW  - Tumor Suppressor Proteins
KW  - Wortmannin
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1074/jbc.M313145200
ER  -