TY  - GEN
AU  - Bruno,Olga
AU  - Brullo,Chiara
AU  - Arduino,Nicoletta
AU  - Schenone,Silvia
AU  - Ranise,Angelo
AU  - Bondavalli,Francesco
AU  - Ottonello,Luciano
AU  - Dapino,Patrizia
AU  - Dallegri,Franco
TI  - Synthesis and biological evaluation of neutrophilic inflammation inhibitors
SN  - 0014-827X
PY  - 2004///0601
KW  - 3',5'-Cyclic-AMP Phosphodiesterases
KW  - antagonists & inhibitors
KW  - 3',5'-Cyclic-GMP Phosphodiesterases
KW  - Anti-Inflammatory Agents, Non-Steroidal
KW  - chemical synthesis
KW  - Benzaldehydes
KW  - Benzoates
KW  - Binding, Competitive
KW  - drug effects
KW  - Cell Separation
KW  - Cyclic AMP
KW  - metabolism
KW  - Cyclic Nucleotide Phosphodiesterases, Type 3
KW  - Cyclic Nucleotide Phosphodiesterases, Type 4
KW  - Cyclic Nucleotide Phosphodiesterases, Type 5
KW  - Cyclopentanes
KW  - Dose-Response Relationship, Drug
KW  - Humans
KW  - Hydroxybenzoate Ethers
KW  - In Vitro Techniques
KW  - Indicators and Reagents
KW  - Neutrophils
KW  - Phosphodiesterase Inhibitors
KW  - Phosphoric Diester Hydrolases
KW  - Rolipram
KW  - Superoxides
KW  - Tumor Necrosis Factor-alpha
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.farmac.2003.08.005
ER  -