Fagan, Karen A

Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase. [electronic resource] - American journal of physiology. Lung cellular and molecular physiology Oct 2004 - L656-64 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1040-0605

10.1152/ajplung.00090.2003 doi


Amides--therapeutic use
Animals
Cardiomegaly--physiopathology
Enzyme Inhibitors--therapeutic use
Hematocrit
Hypertension, Pulmonary--prevention & control
Hypoxia
In Vitro Techniques
Intracellular Signaling Peptides and Proteins
Lung--drug effects
Male
Mice
Mice, Inbred C57BL
Perfusion
Protein Serine-Threonine Kinases--antagonists & inhibitors
Pulmonary Circulation--drug effects
Pyridines--therapeutic use
Vasoconstriction--drug effects
Ventricular Dysfunction, Right--pathology
Ventricular Function, Right--drug effects
rho-Associated Kinases