Tegeder, Irmgard

Specific Inhibition of IkappaB kinase reduces hyperalgesia in inflammatory and neuropathic pain models in rats. [electronic resource] - The Journal of neuroscience : the official journal of the Society for Neuroscience Feb 2004 - 1637-45 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1529-2401

10.1523/JNEUROSCI.3118-03.2004 doi


Active Transport, Cell Nucleus--drug effects
Analgesics--pharmacokinetics
Animals
Anti-Inflammatory Agents--pharmacokinetics
Cells, Cultured
Cyclooxygenase 2
Disease Models, Animal
Dose-Response Relationship, Drug
Enzyme Inhibitors--pharmacokinetics
Formaldehyde
Humans
Hyperalgesia--complications
I-kappa B Kinase
Inflammation--chemically induced
Injections, Intraperitoneal
Interleukin-1--genetics
Isoenzymes--genetics
Male
Membrane Proteins
NF-kappa B--metabolism
Neuralgia--complications
Pain Measurement--drug effects
Prostaglandin-Endoperoxide Synthases--genetics
Protein Serine-Threonine Kinases--antagonists & inhibitors
Rats
Rats, Sprague-Dawley
Spinal Cord--drug effects
Tumor Necrosis Factor-alpha--genetics
Up-Regulation--drug effects
Zymosan