Lead exposure and heat shock inhibit cell proliferation in human HeLa and K562 cells by inducing expression and activity of the heme-regulated eIF-2alpha kinase. [electronic resource]
- Journal of biochemistry, molecular biology, and biophysics : JBMBB : the official journal of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) Dec 2002
- 391-6 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
1025-8140
10.1080/1025814021000036124 doi
Adaptation, Physiological--drug effects Cell Division--drug effects Enzyme Activation--drug effects Gene Expression Regulation, Enzymologic--drug effects HeLa Cells--cytology Heat-Shock Response Hot Temperature Humans K562 Cells--cytology Lead--toxicity eIF-2 Kinase--metabolism