TY - GEN AU - Adikwu,Michael U AU - Yoshikawa,Yukako AU - Takada,Kanji TI - Pharmacodynamic-pharmacokinetic profiles of metformin hydrochloride from a mucoadhesive formulation of a polysaccharide with antidiabetic property in streptozotocin-induced diabetic rat models SN - 0142-9612 PY - 2004///1008 KW - Adhesiveness KW - Animals KW - Blood Glucose KW - analysis KW - Chemistry, Pharmaceutical KW - methods KW - Culture Techniques KW - Diabetes Mellitus, Experimental KW - blood KW - Drug Compounding KW - Drug Delivery Systems KW - Excipients KW - pharmacokinetics KW - Galactose KW - administration & dosage KW - Hypoglycemic Agents KW - Intestinal Mucosa KW - drug effects KW - Male KW - Metformin KW - Plant Gums KW - Rats KW - Rats, Wistar KW - Streptozocin KW - Tensile Strength KW - Tissue Adhesives KW - Treatment Outcome N1 - Publication Type: Comparative Study; Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.biomaterials.2003.09.073 ER -