TY  - GEN
AU  - Tanaka,Yoshiko
AU  - Kobayashi,Hiroshi
AU  - Suzuki,Mika
AU  - Hirashima,Yasuyuki
AU  - Kanayama,Naohiro
AU  - Terao,Toshihiko
TI  - Genetic downregulation of pregnancy-associated plasma protein-A (PAPP-A) by bikunin reduces IGF-I-dependent Akt and ERK1/2 activation and subsequently reduces ovarian cancer cell growth, invasion and metastasis
SN  - 0020-7136
PY  - 2004///0324
KW  - Cell Division
KW  - drug effects
KW  - Down-Regulation
KW  - Enzyme Activation
KW  - Female
KW  - Humans
KW  - Insulin-Like Growth Factor Binding Protein 4
KW  - metabolism
KW  - Insulin-Like Growth Factor I
KW  - pharmacology
KW  - MAP Kinase Signaling System
KW  - Membrane Glycoproteins
KW  - Mitogen-Activated Protein Kinase 1
KW  - Mitogen-Activated Protein Kinase 3
KW  - Mitogen-Activated Protein Kinases
KW  - Neoplasm Invasiveness
KW  - Neoplasm Metastasis
KW  - Oligonucleotides, Antisense
KW  - Ovarian Neoplasms
KW  - Pregnancy-Associated Plasma Protein-A
KW  - genetics
KW  - Protein Serine-Threonine Kinases
KW  - Proto-Oncogene Proteins
KW  - Proto-Oncogene Proteins c-akt
KW  - RNA, Messenger
KW  - Serine Proteinase Inhibitors
KW  - Trypsin Inhibitor, Kunitz Soybean
KW  - Tumor Cells, Cultured
KW  - Urokinase-Type Plasminogen Activator
N1  - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1002/ijc.11700
ER  -