Mechanical compression of cartilage explants induces multiple time-dependent gene expression patterns and involves intracellular calcium and cyclic AMP. [electronic resource]
- The Journal of biological chemistry May 2004
- 19502-11 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0021-9258
10.1074/jbc.M400437200 doi
ADAM Proteins ADAMTS4 Protein Animals Cartilage--chemistry Cartilage, Articular--metabolism Cattle Chondrocytes--physiology Cluster Analysis Collagen--metabolism Collagenases--biosynthesis Cyclic AMP--metabolism Cyclic AMP-Dependent Protein Kinase Type II Cyclic AMP-Dependent Protein Kinases--biosynthesis Cyclooxygenase 2 Egtazic Acid--analogs & derivatives Gene Expression Regulation Isoenzymes--biosynthesis Kinetics Matrix Metalloproteinase 13 Matrix Metalloproteinase 3--biosynthesis Matrix Metalloproteinase 9--biosynthesis Metalloendopeptidases--biosynthesis Models, Genetic Procollagen N-Endopeptidase Prostaglandin-Endoperoxide Synthases--biosynthesis RNA--chemistry RNA, Messenger--metabolism Reverse Transcriptase Polymerase Chain Reaction Signal Transduction Stress, Mechanical Tensile Strength Time Factors Transcription, Genetic Up-Regulation