Nerve growth factor withdrawal-mediated apoptosis in naive and differentiated PC12 cells through p53/caspase-3-dependent and -independent pathways. [electronic resource]
- The Journal of biological chemistry Apr 2004
- 15604-14 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0021-9258
10.1074/jbc.M311500200 doi
Animals Annexin A5--pharmacology Apoptosis Blotting, Western Caspase 3 Caspase 6 Caspase 8 Caspase 9 Caspases--metabolism Cell Cycle Cell Death Cell Differentiation Coloring Agents--pharmacology Cyclin-Dependent Kinase Inhibitor p21 Cyclins--metabolism DNA--chemistry In Situ Nick-End Labeling Indicators and Reagents--pharmacology Models, Biological Nerve Growth Factor--metabolism Neurons--pathology PC12 Cells Proto-Oncogene Proteins--metabolism Proto-Oncogene Proteins c-bcl-2--metabolism RNA, Small Interfering--metabolism Rats Temperature Tetrazolium Salts--pharmacology Time Factors Transfection Trypan Blue--pharmacology Tumor Suppressor Protein p53--metabolism bcl-2-Associated X Protein