Boulay, Anne <br/><br/>
Antitumor efficacy of intermittent treatment schedules with the rapamycin derivative RAD001 correlates with prolonged inactivation of ribosomal protein S6 kinase 1 in peripheral blood mononuclear cells.  [electronic resource] 

 -  Cancer research  Jan 2004 
 - 252-61 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0008-5472 
<br/><br/><label>Standard No.: </label>10.1158/0008-5472.can-3554-2  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Disease Models, Animal<br/>Dose-Response Relationship, Drug<br/>Drug Administration Schedule<br/>Drug Monitoring--methods<br/>Everolimus<br/>Humans<br/>Immunosuppressive Agents--administration & dosage<br/>Leukocytes, Mononuclear--enzymology<br/>MAP Kinase Signaling System--drug effects<br/>Male<br/>Pancreatic Neoplasms--drug therapy<br/>Rats<br/>Rats, Inbred Lew<br/>Ribosomal Protein S6 Kinases, 90-kDa--antagonists & inhibitors<br/>Sirolimus--administration & dosage<br/>Time Factors<br/>Tumor Cells, Cultured