Russell, Laurie K

Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner. [electronic resource] - Circulation research Mar 2004 - 525-33 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1524-4571

10.1161/01.RES.0000117088.36577.EB doi


Adenosine Triphosphate--biosynthesis
Age Factors
Animals
Animals, Newborn
Cardiomyopathy, Dilated--genetics
Disease Models, Animal
Doxycycline--pharmacology
Energy Metabolism
Gene Expression Regulation, Developmental--drug effects
Genes, Synthetic
Mice
Mice, Transgenic
Mitochondria, Heart--physiology
Myocytes, Cardiac--metabolism
Myosin Heavy Chains--genetics
Organ Specificity
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
Promoter Regions, Genetic--genetics
Recombinant Fusion Proteins--physiology
Regulatory Sequences, Nucleic Acid--drug effects
Trans-Activators--biosynthesis
Transcription Factors
Transgenes