TY  - GEN
AU  - Green,Brian D
AU  - Gault,Victor A
AU  - Irwin,Nigel
AU  - Mooney,Mark H
AU  - Bailey,Clifford J
AU  - Harriott,Patrick
AU  - Greer,Brett
AU  - Flatt,Peter R
AU  - O'Harte,Finbarr P M
TI  - Metabolic stability, receptor binding, cAMP generation, insulin secretion and antihyperglycaemic activity of novel N-terminal Glu9-substituted analogues of glucagon-like peptide-1
SN  - 1431-6730
PY  - 2004///0920
KW  - Adenosine Deaminase
KW  - metabolism
KW  - Amino Acid Substitution
KW  - Animals
KW  - Binding, Competitive
KW  - Blood Glucose
KW  - drug effects
KW  - Cell Line, Tumor
KW  - Cricetinae
KW  - Cyclic AMP
KW  - Diabetes Mellitus, Type 2
KW  - drug therapy
KW  - Dipeptidyl Peptidase 4
KW  - Fibroblasts
KW  - Glucagon
KW  - genetics
KW  - Glucagon-Like Peptide 1
KW  - Glucagon-Like Peptide-1 Receptor
KW  - Glucose
KW  - pharmacology
KW  - Glutamine
KW  - chemistry
KW  - Glycoproteins
KW  - Humans
KW  - Hypoglycemic Agents
KW  - Insulin
KW  - blood
KW  - Insulin Secretion
KW  - Islets of Langerhans
KW  - Mice
KW  - Mice, Obese
KW  - Peptide Fragments
KW  - Phenylalanine
KW  - Proline
KW  - Protein Precursors
KW  - Rats
KW  - Receptors, Glucagon
KW  - Spectrometry, Mass, Electrospray Ionization
KW  - Transformation, Genetic
KW  - Tyrosine
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1515/BC.2003.171
ER  -