Green, Brian D <br/><br/>
Metabolic stability, receptor binding, cAMP generation, insulin secretion and antihyperglycaemic activity of novel N-terminal Glu9-substituted analogues of glucagon-like peptide-1.  [electronic resource] 

 -  Biological chemistry  Dec 2003 
 - 1543-51 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1431-6730 
<br/><br/><label>Standard No.: </label>10.1515/BC.2003.171  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adenosine Deaminase--metabolism<br/>Amino Acid Substitution<br/>Animals<br/>Binding, Competitive<br/>Blood Glucose--drug effects<br/>Cell Line, Tumor<br/>Cricetinae<br/>Cyclic AMP--metabolism<br/>Diabetes Mellitus, Type 2--drug therapy<br/>Dipeptidyl Peptidase 4<br/>Fibroblasts--metabolism<br/>Glucagon--genetics<br/>Glucagon-Like Peptide 1<br/>Glucagon-Like Peptide-1 Receptor<br/>Glucose--pharmacology<br/>Glutamine--chemistry<br/>Glycoproteins--metabolism<br/>Humans<br/>Hypoglycemic Agents--metabolism<br/>Insulin--blood<br/>Insulin Secretion<br/>Islets of Langerhans--drug effects<br/>Mice<br/>Mice, Obese<br/>Peptide Fragments--genetics<br/>Phenylalanine--chemistry<br/>Proline--chemistry<br/>Protein Precursors--genetics<br/>Rats<br/>Receptors, Glucagon--metabolism<br/>Spectrometry, Mass, Electrospray Ionization<br/>Transformation, Genetic<br/>Tyrosine--chemistry