TY - GEN AU - De Bosscher,Karolien AU - Hill,Caroline S AU - Nicolás,Francisco J TI - Molecular and functional consequences of Smad4 C-terminal missense mutations in colorectal tumour cells SN - 1470-8728 PY - 2004///0716 KW - ADP-Ribosylation Factor 1 KW - metabolism KW - Active Transport, Cell Nucleus KW - Amino Acid Substitution KW - Cell Division KW - drug effects KW - Cell Nucleus KW - Colorectal Neoplasms KW - DNA-Binding Proteins KW - chemistry KW - Dimerization KW - Forkhead Transcription Factors KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Macromolecular Substances KW - Models, Molecular KW - Mutation, Missense KW - Neoplasm Proteins KW - Nerve Growth Factors KW - Point Mutation KW - Protein Binding KW - Protein Conformation KW - Protein Structure, Tertiary KW - Signal Transduction KW - Smad Proteins KW - Smad2 Protein KW - Smad3 Protein KW - Smad4 Protein KW - Structure-Activity Relationship KW - Trans-Activators KW - Transcription Factors KW - Transcription, Genetic KW - Transforming Growth Factor beta KW - pharmacology KW - Xenopus Proteins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1042/BJ20031886 ER -