Bakker, Jan <br/><br/>
Administration of the nitric oxide synthase inhibitor NG-methyl-L-arginine hydrochloride (546C88) by intravenous infusion for up to 72 hours can promote the resolution of shock in patients with severe sepsis: results of a randomized, double-blind, placebo-controlled multicenter study (study no. 144-002).  [electronic resource] 

 -  Critical care medicine  Jan 2004 
 - 1-12 p.  digital 
<br/><br/> Publication Type: Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0090-3493 
<br/><br/><label>Standard No.: </label>10.1097/01.CCM.0000105118.66983.19  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Aged<br/>Aged, 80 and over<br/>Critical Care--methods<br/>Dose-Response Relationship, Drug<br/>Double-Blind Method<br/>Drug Administration Schedule<br/>Female<br/>Follow-Up Studies<br/>Hemodynamics--drug effects<br/>Humans<br/>Infusions, Intravenous<br/>Intensive Care Units<br/>Male<br/>Middle Aged<br/>Nitric Oxide Synthase--antagonists & inhibitors<br/>Oxygen Consumption--drug effects<br/>Probability<br/>Reference Values<br/>Risk Assessment<br/>Severity of Illness Index<br/>Shock, Septic--drug therapy<br/>Survival Analysis<br/>Treatment Outcome<br/>omega-N-Methylarginine--administration & dosage