TY - GEN AU - Federici,Massimo AU - Pandolfi,Assunta AU - De Filippis,Elena Anna AU - Pellegrini,Giuliana AU - Menghini,Rossella AU - Lauro,Davide AU - Cardellini,Marina AU - Romano,Mario AU - Sesti,Giorgio AU - Lauro,Renato AU - Consoli,Agostino TI - G972R IRS-1 variant impairs insulin regulation of endothelial nitric oxide synthase in cultured human endothelial cells SN - 1524-4539 PY - 2004///0209 KW - Cells, Cultured KW - Endothelium, Vascular KW - cytology KW - Gene Expression Regulation, Enzymologic KW - Humans KW - Insulin KW - pharmacology KW - Insulin Receptor Substrate Proteins KW - Mitogen-Activated Protein Kinases KW - metabolism KW - Nitric Oxide Synthase KW - genetics KW - Nitric Oxide Synthase Type III KW - Phosphatidylinositol 3-Kinases KW - Phosphoproteins KW - Phosphorylation KW - drug effects KW - Polymorphism, Genetic KW - Protein Serine-Threonine Kinases KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-akt KW - RNA, Messenger KW - Signal Transduction N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1161/01.CIR.0000109498.77895.6F ER -