TY - GEN AU - Zhou,Wenbo AU - Freed,Curt R TI - Tyrosine-to-cysteine modification of human alpha-synuclein enhances protein aggregation and cellular toxicity SN - 0021-9258 PY - 2004///0519 KW - Adenoviridae KW - genetics KW - Animals KW - Apoptosis KW - Blotting, Western KW - Cell Line KW - Cell Survival KW - Cloning, Molecular KW - Cysteine KW - chemistry KW - Detergents KW - pharmacology KW - Dimerization KW - Electrophoresis, Polyacrylamide Gel KW - Humans KW - Immunohistochemistry KW - Magnetic Resonance Spectroscopy KW - Mice KW - Microscopy, Fluorescence KW - Mutagenesis, Site-Directed KW - Mutation KW - Nerve Tissue Proteins KW - Neurons KW - metabolism KW - Nitrogen KW - Octoxynol KW - Oxidative Stress KW - Oxygen KW - Phenylalanine KW - Plasmids KW - Protein Binding KW - Proteins KW - Rats KW - Recombinant Proteins KW - Synucleins KW - Time Factors KW - Transfection KW - Tyrosine KW - alpha-Synuclein KW - beta-Synuclein N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1074/jbc.M307563200 ER -