Tyrosine-to-cysteine modification of human alpha-synuclein enhances protein aggregation and cellular toxicity. [electronic resource]
- The Journal of biological chemistry Mar 2004
- 10128-35 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9258
10.1074/jbc.M307563200 doi
Adenoviridae--genetics Animals Apoptosis Blotting, Western Cell Line Cell Survival Cloning, Molecular Cysteine--chemistry Detergents--pharmacology Dimerization Electrophoresis, Polyacrylamide Gel Humans Immunohistochemistry Magnetic Resonance Spectroscopy Mice Microscopy, Fluorescence Mutagenesis, Site-Directed Mutation Nerve Tissue Proteins--chemistry Neurons--metabolism Nitrogen--chemistry Octoxynol--pharmacology Oxidative Stress Oxygen--metabolism Phenylalanine--chemistry Plasmids--chemistry Protein Binding Proteins--chemistry Rats Recombinant Proteins--chemistry Synucleins Time Factors Transfection Tyrosine--chemistry alpha-Synuclein beta-Synuclein