Senior, Suzanne J

Acetylene-based analogues of thiolactomycin, active against Mycobacterium tuberculosis mtFabH fatty acid condensing enzyme. [electronic resource] - Bioorganic & medicinal chemistry letters Jan 2004 - 373-6 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0960-894X

10.1016/j.bmcl.2003.10.061 doi


Acetylene--analogs & derivatives
Acetyltransferases--antagonists & inhibitors
Bacterial Proteins--antagonists & inhibitors
Enzyme Inhibitors--chemistry
Fatty Acid Synthase, Type II
Fatty Acid Synthases--antagonists & inhibitors
Multienzyme Complexes--antagonists & inhibitors
Mycobacterium tuberculosis--drug effects
Thiophenes--chemistry