Campiani, Giuseppe <br/><br/>
Pyrrolo[1,3]benzothiazepine-based serotonin and dopamine receptor antagonists. Molecular modeling, further structure-activity relationship studies, and identification of novel atypical antipsychotic agents.  [electronic resource] 

 -  Journal of medicinal chemistry  Jan 2004 
 - 143-57 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm0309811  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antipsychotic Agents--chemical synthesis<br/>Avoidance Learning--drug effects<br/>Benzothiepins--chemical synthesis<br/>Catalepsy--chemically induced<br/>Cognition Disorders--chemically induced<br/>Dopamine Antagonists--chemical synthesis<br/>Humans<br/>Male<br/>Mice<br/>Models, Molecular<br/>Motor Activity--drug effects<br/>Pituitary Gland, Anterior--drug effects<br/>Prolactin--metabolism<br/>Pyrroles--chemical synthesis<br/>Rats<br/>Rats, Inbred F344<br/>Rats, Wistar<br/>Receptors, Dopamine D1--metabolism<br/>Receptors, Dopamine D2--metabolism<br/>Receptors, Dopamine D3<br/>Receptors, Serotonin, 5-HT2--metabolism<br/>Serotonin Antagonists--chemical synthesis<br/>Structure-Activity Relationship<br/>Thiazepines--chemical synthesis