Tower, Grant B

The 2G single nucleotide polymorphism (SNP) in the MMP-1 promoter contributes to high levels of MMP-1 transcription in MCF-7/ADR breast cancer cells. [electronic resource] - Breast cancer research and treatment Nov 2003 - 75-82 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0167-6806

10.1023/B:BREA.0000003948.14026.7c doi


Binding Sites--genetics
Breast Neoplasms--genetics
Cell Line, Tumor--drug effects
Collagen Type I--metabolism
Down-Regulation
Enzyme Inhibitors--pharmacology
Flavonoids--pharmacology
Gene Expression Regulation, Enzymologic--drug effects
Humans
Imidazoles--pharmacology
In Vitro Techniques
Matrix Metalloproteinase 1--genetics
Mitogen-Activated Protein Kinase 1--antagonists & inhibitors
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinases--antagonists & inhibitors
Polymorphism, Single Nucleotide
Promoter Regions, Genetic--genetics
Pyridines--pharmacology
RNA, Messenger--genetics
Transcription Factor AP-1--metabolism
Transcription, Genetic
Transfection