TY - GEN AU - Cassano,Adam G AU - Anderson,Vernon E AU - Harris,Michael E TI - Understanding the transition states of phosphodiester bond cleavage: insights from heavy atom isotope effects SN - 0006-3525 PY - 2004///0217 KW - Base Composition KW - Binding Sites KW - Catalysis KW - DNA KW - chemistry KW - Hydrogen-Ion Concentration KW - Hydrolysis KW - Hydroxides KW - Ions KW - Isotopes KW - Kinetics KW - Models, Chemical KW - Nucleic Acids KW - RNA KW - Thionucleotides N1 - Publication Type: Journal Article; Review UR - https://doi.org/10.1002/bip.10517 ER -