TY - GEN AU - Schmidt,C Max AU - Wang,Yufang AU - Wiesenauer,Chad TI - Novel combination of cyclooxygenase-2 and MEK inhibitors in human hepatocellular carcinoma provides a synergistic increase in apoptosis SN - 1091-255X PY - 2004///0527 KW - Adenocarcinoma KW - drug therapy KW - Apoptosis KW - drug effects KW - Butadienes KW - pharmacology KW - Carcinoma, Hepatocellular KW - Cell Cycle KW - Cell Division KW - Cell Line, Tumor KW - Cyclooxygenase 1 KW - Cyclooxygenase 2 KW - Dinoprostone KW - metabolism KW - Drug Synergism KW - Enzyme Inhibitors KW - Humans KW - Isoenzymes KW - antagonists & inhibitors KW - Liver Neoplasms KW - Membrane Proteins KW - Mitogen-Activated Protein Kinase Kinases KW - Mitogen-Activated Protein Kinases KW - Nitriles KW - Nitrobenzenes KW - Pancreatic Neoplasms KW - Prostaglandin-Endoperoxide Synthases KW - Signal Transduction KW - Sulfonamides N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.gassur.2003.09.009 ER -