TY  - GEN
AU  - Sawada,Hideyuki
AU  - Kohno,Ryuichi
AU  - Kihara,Takeshi
AU  - Izumi,Yasuhiko
AU  - Sakka,Noriko
AU  - Ibi,Masakazu
AU  - Nakanishi,Miki
AU  - Nakamizo,Tomoki
AU  - Yamakawa,Kentarou
AU  - Shibasaki,Hiroshi
AU  - Yamamoto,Noriyuki
AU  - Akaike,Akinori
AU  - Inden,Masatoshi
AU  - Kitamura,Yoshihisa
AU  - Taniguchi,Takashi
AU  - Shimohama,Shun
TI  - Proteasome mediates dopaminergic neuronal degeneration, and its inhibition causes alpha-synuclein inclusions
SN  - 0021-9258
PY  - 2004///0519
KW  - 1-Methyl-4-phenylpyridinium
KW  - pharmacology
KW  - Acetylcysteine
KW  - analogs & derivatives
KW  - Animals
KW  - Brain
KW  - metabolism
KW  - Caspase 3
KW  - Caspase Inhibitors
KW  - Caspases
KW  - Cysteine Endopeptidases
KW  - Dopamine
KW  - Dopamine Agents
KW  - Dose-Response Relationship, Drug
KW  - Enzyme Inhibitors
KW  - Herbicides
KW  - Immunoblotting
KW  - Immunohistochemistry
KW  - Ions
KW  - L-Lactate Dehydrogenase
KW  - Leupeptins
KW  - MAP Kinase Signaling System
KW  - Male
KW  - Mitochondria
KW  - Mitogen-Activated Protein Kinase 1
KW  - Mitogen-Activated Protein Kinase 3
KW  - Mitogen-Activated Protein Kinases
KW  - Multienzyme Complexes
KW  - antagonists & inhibitors
KW  - Nerve Tissue Proteins
KW  - Neurons
KW  - Phosphorylation
KW  - Proteasome Endopeptidase Complex
KW  - Rats
KW  - Rats, Wistar
KW  - Rotenone
KW  - Synucleins
KW  - Time Factors
KW  - Ubiquitin
KW  - alpha-Synuclein
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1074/jbc.M308434200
ER  -