TY - GEN AU - Darwin,K Heran AU - Ehrt,Sabine AU - Gutierrez-Ramos,José-Carlos AU - Weich,Nadine AU - Nathan,Carl F TI - The proteasome of Mycobacterium tuberculosis is required for resistance to nitric oxide SN - 1095-9203 PY - 2003///1229 KW - Adenosine Triphosphatases KW - antagonists & inhibitors KW - Amide Synthases KW - Animals KW - Antitubercular Agents KW - pharmacology KW - Bacterial Proteins KW - genetics KW - Carrier Proteins KW - Colony Count, Microbial KW - Cysteine Endopeptidases KW - DNA Transposable Elements KW - Genes, Bacterial KW - Genetic Complementation Test KW - Hydrogen Peroxide KW - Hydrogen-Ion Concentration KW - Macrophages KW - microbiology KW - Mice KW - Mice, Inbred C57BL KW - Microbial Sensitivity Tests KW - Multienzyme Complexes KW - Mutation KW - Mycobacterium tuberculosis KW - drug effects KW - Nitric Oxide KW - metabolism KW - Nitric Oxide Synthase KW - Nitric Oxide Synthase Type II KW - Nitrites KW - Oxidative Stress KW - Protease Inhibitors KW - Proteasome Endopeptidase Complex KW - Tuberculosis KW - Virulence N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1126/science.1091176 ER -