Erber, Ralf

Combined inhibition of VEGF and PDGF signaling enforces tumor vessel regression by interfering with pericyte-mediated endothelial cell survival mechanisms. [electronic resource] - FASEB journal : official publication of the Federation of American Societies for Experimental Biology Feb 2004 - 338-40 p. digital

Publication Type: Journal Article

1530-6860

10.1096/fj.03-0271fje doi


Animals
Apoptosis
Cell Survival--drug effects
Hypoxia
Indoles--pharmacology
Microcirculation--drug effects
Models, Biological
Neoplasms--blood supply
Neovascularization, Pathologic--drug therapy
Oxindoles
Pericytes--cytology
Platelet-Derived Growth Factor--antagonists & inhibitors
Propionates
Pyrroles--pharmacology
Receptor, Platelet-Derived Growth Factor beta--antagonists & inhibitors
Signal Transduction--drug effects
Vascular Endothelial Growth Factor A--antagonists & inhibitors
Vascular Endothelial Growth Factor Receptor-2--antagonists & inhibitors